Faculty and Their Research

Richard M. Amasino email
Regulation of plant development; specifically, floral induction and plant senescence

Aseem Z. Ansari email
Studying the regulation of gene expression at the interface of chemistry, biology and genomics

Alan D. Attie email
Molecular genetics of diabetes & insulin resistance; cell biology of lipoprotein assembly, cholesterol trafficking

Jon Audhya  email
Mechanisms of membrane trafficking; regulation of growth factor signaling; live-cell imaging; membrane remodeling during development of the nematode Caenorhabditis elegans

Sebastian Y. Bednarek email
Plant cell biology; intracellular protein trafficking, membrane biogenesis

Paul Bertics email
Regulation of cellular growth and differentiation; enzymology of protein kinases; biochemical characterization and interaction of growth factor, growth hormone, and purinergic receptors; endotoxin signaling and macrophage activation

David Brow email
Nuclear steps in gene expression; transcription by RNA polymerases II and III; RNA dynamics in pre-mRNA splicing

Samuel E. Butcher email
RNA Structure, Function and Dynamics;NMR Spectroscopy of RNA and Macromolecular Complexes; Biochemistry of RNA catalysis

Margaret Clagett-Dame email
Molecular mechanism of action of vitamin A in embryonic development, vitamin A and neuronal survival and differentiation, retinoids in chemoprevention and chemotherapy

W. Wallace Cleland email
Kinetics and mechanisms of enzymes; isotope effects

Joshua Coon email
Development and application of proteomics-based technologies to monitor protein expression, mRNA editing, and cellular signaling

Michael M. Cox email
Molecular biology and enzymology of genetic recombination and DNA repair

Gheorghe Craciun  email
Mathematical and computational models of complex biochemical systems

Elizabeth A. Craig email
Protein folding in the cell ? the function of molecular chaperones in facilitating protein folding and protein translocation across membranes

James Dahlberg email
RNA, processing and transport; nuclear export; microRNA control

Hector F. DeLuca email
Molecular function of vitamins and hormones, metabolism of vitamins A and D

John Denu email
Mechanism and biological function of reversible protein modifications in signal transduction, chromatin dynamics and gene activation

Robert Fillingame email
Membrane biochemistry; mechanism of H+-transporting, rotary ATP synthase of oxidative phosphorylation

Brian G. Fox email
Biochemical, catalytic, and spectroscopic studies of redox active enzymes; protein engineering

Catherine Fox email
Replication, structure, and expression of eukaryotic chromosomes; conserved mechanisms linking transcription, cell cycle, and cell differentiation

Perry A. Frey email
Mechanisms of enzyme and coenzyme action; stereochemistry and mechanisms of phospho- and nucleotidyl transferase action; structure and function of multienzyme complexes

Paul D. Friesen email
Molecular biology of eukaryotic DNA viruses, regulation of gene expression, programmed cell death (apoptosis), and retrotransposons

Colleen E. Hayes email
Molecular mechanisms that regulate immune responses

Hazel M. Holden email
Three-dimensional structures of proteins by x-ray crystallographic analysis

Christina Hull email
Molecular biology of the human fungal pathogen Cryptococcus neoformans; sexual development; cell identity determination; gene regulation; protein-DNA interactions

Ross B. Inman email
Replication and structure of DNA

James Keck email
Structure-function studies of DNA replication, recombination, and repair proteins

Laura L. Kiessling email
Biomolecular recognition processes; the chemistry and biology of protein-saccharide interactions

Patricia Kiley email
Transcriptional regulation; signal transduction of oxygen deprivation; Fe-S cluster assembly and regulation

Judith Kimble email
Regulation of development in the nematode Caenorhabditis elegans

Robert Landick email
RNA polymerase structure/function; regulation of transcript elongation in bacteria and humans

John L. Markley email
NMR spectroscopy and its biological applications; structure function relationships in proteins; stable-isotope- assisted multinuclear NMR spectroscopy; processing and analysis of multi-dimensional NMR data

Thomas F. J. Martin email
Mechanisms of hormone action; signal transduction and second messengers; regulation of hormone and neurotransmitter secretion; inositol phospholipid biochemistry

Julie Mitchell email
Computational analysis of protein interactions and macromolecular shape features

Deane Mosher email
Structure and function of extracellular proteins involved in cell migration and differentiation with emphases on thrombosis, hemostasis, and white cell trafficking

David L. Nelson email
Biochemistry of behavior in Paramecium: Role of Ca2+, cyclic nucleotides, and protein kinases

James M. Ntambi email
Cellular differentiation and hormonal and dietary regulation of the stearoyl-CoA desaturase (SCD) genes

Ann C. Palmenberg email
Molecular biology of RNA picornaviruses; protein translation, proteolytic processing; RNA synthesis; viral pathogenesis; viral vaccines, vaccine vectors; computer-based sequence analysis

George N. Phillips, Jr. email
Structure and dynamics of proteins, computational biology

J. Wesley Pike email
Transcriptional mechanisms of steroid hormone action in the skeleton

Ronald T. Raines email
Chemical biology, protein design and engineering, enzymology

Ivan Rayment email
Structure and function of proteins by x-ray diffraction analysis

M. Thomas Record, Jr. email
Biophysical studies of protein-nucleic acid interactions in transcription initiation in vitro and in E. coli; computational and experimental studies of polyelectrolyte properties of nucleic acids and their complexes

George H. Reed email
Activation of enzymic reactions by metal ions; biophysical applications of spectroscopy

Michael Sheets email
Regulation of vertebrate development and cell differentiation by molecular signaling pathways

Michael R. Sussman email
Signal transduction in eukaryotes, development of genomic technologies, plasma membrane receptors and ion transporters, Arabidopsis thaliana.

Douglas B. Weibel email
Understanding the behavior and physiology of microbes; biological engineering

Marvin P. Wickens email
Molecular genetics; RNA and RNA-protein interactions; developmental biology

Christiane Wiese email
Molecular mechanisms of mitotic spindle assembly and microtubule nucleation; cell-cycle dependent regulation of spindle assembly proteins; centrosome structure and function